Dimethyl Sulfate → HCID 178502517, compound

Participants

Reaction Steps

To a mixture of 3-imino-(4-methoxyphenyl)methyl-4-(3-carbomethoxythioureido)benzophenone (4.47 g.; 0.01 mol) in 1,2-dimethoxyethane (50 ml.) there is added calcium hydride (0.42 g.; 0.01 mol). The mixture is refluxed for one hour and is cooled to room temperature. To the mixture there is added dimethylsulfate (1.26 g.; 0.01 mol). The mixture is stirred at room temperature for one hour and is poured into an excess of ice water. The suspension formed is filtered and the filter cake dried to afford 3-imino-(4-methoxyphenyl)methyl-4-(3-carbomethoxy-S-methylisothioureido)benzophenone.

Provenance & Evidence