HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → N-[4-(hexadecylamino)benzoyl]urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | 4-Hexadecylaminobenzoyl chloride hydrochloride | HCID 13255322 | — |
| Reactant | Urea, monosodium salt | HCID 86736265 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-[4-(hexadecylamino)benzoyl]urea | HCID 20437348 | — |
Reaction Steps
The 12.6 g. of 4-(hexadecylamino)benzoyl chloride hydrochloride in methylene chloride is added to 5 g. of sodium urea in 30 ml. of acetone and the mixture is stirred at 20° C. for 18 hours. Dilute alkali is added and the solid washed with alkaline aqueous acetone. Recrystallization from ethanol gives pure white crystals of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04242273 |
| Source dataset | uspto-grants-1980_12 |
| ORD ID | ord-7545ce9dbbde445098de3e86452bb47c |
| Source note | uspto-grants-1980_12 |