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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1733515Generated: October 25, 2026

Timonacic → 3-[4-(Hexadecylamino)benzoyl]-4-carboxythiazolidine

https://huagongshe.com/reaction/1733515

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTimonacicHCID 9934—
Reactant3-[4-(Hexadecylamino)benzoyl]-4-carboethoxythiazolidineHCID 20437342—
SolventAcetone sodium bicarbonateHCID 86737261—
Product3-[4-(Hexadecylamino)benzoyl]-4-carboxythiazolidineHCID 20437365—

Reaction Steps

By means of the alkaline hydrolysis method of Example 7, the ethyl ester of Example 21 is converted to the subject carboxylic acid. This acid is also prepared using the procedure of Example 21 except that the acylation of the thiazolidine-4-carboxylic acid is carried out in aqueous acetone sodium bicarbonate solution.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04242273
Source datasetuspto-grants-1980_12
ORD IDord-346a798835094e4b8ffafaca0534f146
Source noteuspto-grants-1980_12