Ammonium Hydroxide → HCID 53721589, compound

Participants

Reaction Steps

A solution of (6) (2.54 g, 7.7 mmole) in 1 N HCl (30 ml) was heated on the steam bath for 30 minutes. The cooled solution was made basic with concentrated NH4OH and extracted with three portions of chloroform. The chloroform extracts were evaporated to give a crystalline residue. The residue was dissolved in hot acetone and cooled. Crystals (1.29 g) of the hemi-acetone solvate of (4a) were collected after cooling. Recrystallization from acetone gave analytically pure (4a) as hemi-acetone solvate, mp 166°-167°, identical with material prepared previously.

Provenance & Evidence