反应详情

温度

0 °C

12.7 parts of 3-hydroxy-2-cyanodihydrothiophene are dissolved in 100 parts by volume of chloroform and 200 parts by volume of a 4 percent strength by weight solution of diazomethane in ether are added at 0° C. The solution is stirred for 12 hours at 0° C. and is concentrated under reduced pressure. The residue is distilled. 10.1 parts (72% of theory) of 3-methoxy-2-cyanodihydrothiophene of boiling point 82°-83° C./0.35 mbar are obtained.

1. additionare added at 0° C
2. concentrationis concentrated under reduced pressure
3. distillationThe residue is distilled