Sodium Hydroxide → HCID 54300440, compound

HRID 1733729Notes

Reaction equation

HRID 1733729 reaction equation
[O:1]1[C:6]([C:7](=[N:13][O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[C:8]([O:10]CC)=[O:9])=[CH:5][S:4][CH2:3][CH2:2]1.[OH-].[Na+]>CO>[O:1]1[C:6]([C:7](=[N:13][O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[C:8]([OH:10])=[O:9])=[CH:5][S:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 53819662HCID 53819662, compound

Product 1

HCID 54300440HCID 54300440, compoundYield 25.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Ethyl 2-(2,3-dihydro-1,4-oxathiin-6-yl)-2-n-hexyloxyiminoacetate (mixture of syn isomer and anti isomer, 186.8 g.), 1 N aqueous solution of sodium hydroxide (472 ml.) and methanol (1.8 l.) were stirred at room temperature for 35 minutes and the insoluble substance was removed by filtration. The filtrate was stirred at room temperature for 43 hours and treated in a similar manner to that of Exampl I-(iii) to give 2-(2,3-dihydro-1,4-oxathiin-6-yl)-2-n-hexyloxyiminoacetic acid (syn isomer, 43 g.)

Workup

  1. customthe insoluble substance was removed by filtration
  2. additiontreated in a similar manner to that of Exampl I-(iii)

Sources & evidence

ORD record
ord-e5b444d09ce74f00959f639adb5d2e80
Source dataset
uspto-grants-1980_12
Patent number
US04242510

Reaction notes

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