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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1733755Generated: October 25, 2026

2-Cyclopenten-1-one, 4-hydroxy-3-methyl-2-(2-propen-1-yl)- → alpha-Cyano-3-phenoxybenzyl (1R,cis)-2,2-dimethyl-3-(-2-(isopropoxyimino)propyl)cyclopropanecarboxylat

https://huagongshe.com/reaction/1733755

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Cyclopenten-1-one, 4-hydroxy-3-methyl-2-(2-propen-1-yl)-HCID 11083—
ReactantBenzenemethanol, 2,6-dichloro-HCID 27156—
ReactantN-(Hydroxymethyl)-3,4,5,6-tetrahydrophthalimideHCID 78597—
Reactant3-Phenoxy-alpha-ethynylbenzylalcoholHCID 12919092—
Reactantalpha-cyano-3-phenoxybenzyl (1R,cis)-2,2-dimethyl-3-(2-(neopentoxyimino)propyl)cyclopropanecarboxylateHCID 53762777—
Reactant3-phenoxybenzyl (1R,cis)-2,2-dimethyl-3-(2-(isobutoxyimino)propyl)cyclopropanecarboxylateHCID 54499472—
Reactantalpha-cyano-3-phenoxybenzyl (1R,cis)-2,2-dimethyl-3-(2-(cyclopropylmethoxyimino)propyl)cyclopropanecarboxylateHCID 86737170—
Reactantalpha-cyano-3-phenoxybenzyl (1R,cis)-2,2-dimethyl-3-(2-(cyclobutylmethoxyimino)propyl)cyclopropanecarboxylateHCID 86737171—
Productalpha-Cyano-3-phenoxybenzyl (1R,cis)-2,2-dimethyl-3-(-2-(isopropoxyimino)propyl)cyclopropanecarboxylatHCID 53742917—

Reaction Steps

Following procedures similar to Embodiment II above: α-cyano -3-phenoxybenzyl (1R,cis)-2,2-dimethyl-3-(2-(neopentoxyimino)propyl)cyclopropanecarboxylate, 3-phenoxybenzyl (1R,cis)-2,2-dimethyl-3-(2-(isobutoxyimino)propyl)cyclopropanecarboxylate, α-cyano-3-phenoxybenzyl (1R,cis)-2,2-dimethyl-3-(2-(cyclopropylmethoxyimino)propyl)cyclopropanecarboxylate, α-cyano-3-phenoxybenzyl (1R,cis)-2,2-dimethyl-3-(2-(cyclobutylmethoxyimino)propyl)cyclopropanecarboxylate are prepared as well as the corresponding esters in the racemic and (1R,trans) form and similar esters with other alcohols: α-ethynyl-3-phenoxybenzyl alcohol, 3,4,5,6-tetrahydrophthalimidomethyl alcohol, 2,6-dichlorobenzyl alcohol, 2-chloro-4-phenyl-2-butenl-o1 and allethrolone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04242521
Source datasetuspto-grants-1980_12
ORD IDord-ee2702e9dd3e44b1b8632b1eefac668c
Source noteuspto-grants-1980_12