Hydrochloric Acid → 2-(2-Hydroxyethylthio)thioxanthone

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Reaction Steps

5.6 g. (0.0225 mol) of 2-chlorothioxanthone and 2.6 g. (0.0225 mol) of the potassium salt of 2-mercaptoethanol are stirred for 18 hours in 20 mol of N,N-dimethylacetamide at 100° C. The reaction mixture is then poured into 2N hydrochloric acid and extracted with ethyl acetate. After conventional work-up and chromatographic purification, 3.5 g. of the analytically pure compound IIIaof melting point 94° C. are obtained.

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