HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrophenol → 1-(2-Bromoethoxy)-4-nitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrophenol | HCID 980 | — |
| Reactant | 1,1-Dibromoethane | HCID 11201 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-(2-Bromoethoxy)-4-nitrobenzene | HCID 235987 | — |
Reaction Steps
1.97 g of the sodium salt of p-nitrophenol(0.01 mol), 2.16 ml of dibromoethane (0.025 mol) and 0.5 g of potassium carbonate were taken in 50 ml of dry acetone (4A activated molecular sieves) and refluxed overnight. Potassium carbonate was filtered and the solvent was removed by rotary evaporation to yield 4-(2-bromoethoxy)nitrobenzene (L) in almost quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05532138 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-689d495098004ac29fbd4ce7e178138f |
| Source note | uspto-grants-1996_07 |