Triethylamine → HCID 19438777, compound

Participants

Reaction Steps

To a solution of 4-(1H-imidazol-1-yl)-aniline (14 g; ~88.2 mmol) in 400 ml dry tetrahydrofuran was added dry triethylamine (14.0 ml; ~102 mmol). Ethoxalyl chloride (11.2 ml; 100 mmol) was added dropwise and the reaction mixture was stirred for 2 h. The solvent was removed under reduced pressure, and the residue was stirred with water to give the title compound (19.2 g; 85%). M.p. 177°-180° C.

Provenance & Evidence