Sulfuric Acid → HCID 19438778, compound

Participants

Reaction Steps

To a solution of 0.94 g (~3.5 mmol) of 7-(1H-Imidazol-1-yl)[1,2,4]triazolo [4,3-a]quinoxaline-1,4(2H,5H)-dione in 7.5 ml concentrated (95-97%) sulfuric acid was added first 1.22 g (~3,9 mmol) silver sulfate and then 0.2 ml (~3.9 mmol) bromine. Stirring was continued at 24° C. for 48 h. The reaction mixture was filtered from silver bromide and then poured into 40 ml ice-water. The precipitate was filtered off to give a crude product. To a solution of the crude product in water was added 4N sodium hydroxide to pH=6 to give the title compound as a precipitate (0.42 g; 35%). M.p.>300° C. (decomp.).

Provenance & Evidence