Benzyl Bromide → HCID 19438782, compound

Participants

Reaction Steps

To a solution of 5.3 g (~16.3 mmol) of 1-hydroxy-6-(2-methyl-1H-imidazol-1-yl)-7-trifluoromethylquinoxaline-2,3(1H,4H)-dione in a mixture of 80 ml ethanol and 80 ml 1M potassium dihydrogen phosphate buffer pH 7.4 was added 2.1 ml (17.7 mmol) benzylbromide. Stirring was continued at 25° C. for 1 h. The precipitate was filtered off and washed with water and a little ice-cooled ethanol to give the title compound (5.2 g; 78%). M.p. 156° C. (decomp.).

Provenance & Evidence