Ammonium formate → HCID 86749592, compound

Participants

Reaction Steps

Following the general procedure described in Example 9, Part A, the product of Example 18 (1.0 g, 2.9 mmol), 10% palladium on charcoal (1.0 g), and ammonium formate (2 g) were reacted in methanol (75 mL) to afford the product, a white solid (0.6 g): mp 174°-175° C.; NMR (CDCl3, 300 MHz): 7.5-7.4 (m, 2H), 7.1-6.9 (m, 2H), 3.2-3.0 (m, 2H), 2.8-2.6 (m, 1H), 2.4-2.3 (m, 1H), 2.0-1.0 (m, 25H); MS:249; Anal. Calcd for C15H20FNO.3H2O:C, 70.73, H, 8.23, N, 5.50, F, 7.45; Found: C, 70.82, 70.89, H, 8.10, 8.04, N, 5.14, 5.20, F, 7.08, 6.92.

Provenance & Evidence