2-Chloro-5-nitrobenzoic acid → Benzoyl chloride, 2-chloro-5-nitro-

HRID 1733950Notes

Reaction equation

[Cl:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][C:3]=1[C:4](O)=[O:5].S(Cl)([Cl:16])=O>>[Cl:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][C:3]=1[C:4]([Cl:16])=[O:5]

Participants

Reactant 2

HCID 172872-Chloro-5-nitrobenzoic acid

HCID 24386Thionyl Chloride

Product 1

HCID 117637Benzoyl chloride, 2-chloro-5-nitro-

Procedure

As described for Reference Example 21, 5.0 g of 2-chloro-5-nitrobenzoic acid is reacted with 50 ml of thionyl chloride to give 5.6 g of the product as an off-white solid.

Sources & evidence

ORD record: ord-ed840a0dbd314e3baafa7ac657aa19d2
Source dataset: uspto-grants-1996_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05532235

Reaction notes

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