2-Methylbenzoyl chloride → HCID 44374839, compound

HRID 1734001Notes

Reaction equation

HRID 1734001 reaction equation
[CH3:1][N:2]1[CH:11]=[C:10]2[C:4]([C:5]3[S:23][CH:22]=[CH:21][C:6]=3[N:7]([C:12](=[O:20])[C:13]3[CH:18]=[CH:17][C:16]([NH2:19])=[CH:15][CH:14]=3)[CH2:8][CH2:9]2)=[N:3]1.[CH3:24][C:25]1[CH:33]=[CH:32][CH:31]=[CH:30][C:26]=1[C:27](Cl)=[O:28]>>[CH3:1][N:2]1[CH:11]=[C:10]2[C:4]([C:5]3[S:23][CH:22]=[CH:21][C:6]=3[N:7]([C:12]([C:13]3[CH:14]=[CH:15][C:16]([NH:19][C:27](=[O:28])[C:26]4[CH:30]=[CH:31][CH:32]=[CH:33][C:25]=4[CH3:24])=[CH:17][CH:18]=3)=[O:20])[CH2:8][CH2:9]2)=[N:3]1

Participants

3

Reactant 2

HCID 702762-Methylbenzoyl chlorideHCID 19699068HCID 19699068, compound

Product 1

HCID 44374839HCID 44374839, compound

Procedure

As described for Example 5, 2,4,5,6-tetrahydro-2-methyl -6-(4-aminobenzoyl)pyrazolo[3,4-d]thieno[3,2-b]azepine is reacted with 2-methylbenzoyl chloride to give the product as crystals (from ethyl acetate), m.p. 257°-260° C.

Workup

  1. customto give the product as crystals (from ethyl acetate), m.p. 257°-260° C.

Sources & evidence

ORD record
ord-d4731f47f7394cedbd04e534aa61a101
Source dataset
uspto-grants-1996_07
Patent number
US05532235

Reaction notes

Loading…