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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1734106Generated: October 27, 2026

Glutaric anhydride → 6-Amidino-2-naphthyl 5-(4-carboxybutyrylaminomethyl)furan-2-carboxylate hydrochloride

https://huagongshe.com/reaction/1734106

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlutaric anhydrideHCID 7940—
ReactantSodium AcetateHCID 517045—
Reactant6-Amidino-2-naphthyl 5-aminomethylfuran-2-carboxylate dihydrochlorideHCID 22398815—
SolventDimethylformamideHCID 6228—
Product6-Amidino-2-naphthyl 5-(4-carboxybutyrylaminomethyl)furan-2-carboxylate hydrochlorideHCID 9825477—

Reaction Conditions

Temperature20 °C

Reaction Steps

To 8 g of 6-amidino-2-naphthyl 5-aminomethyl-furan-2-carboxylate dihydrochloride, 3.6 g of glutaric anhydride and 1.72 g of anhydrous sodium acetate was added 50 ml of DMF, and the resulting mixture was stirred at 20° C. for 20 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05532267
Source datasetuspto-grants-1996_07
ORD IDord-4c6db2b0b6b546b5b2cbb51fc5bfd836
Source noteuspto-grants-1996_07