Carbon Dioxide → 3-Hydroxy-2-naphthoic acid

Participants

Reaction Conditions

Reaction Steps

A stainless steel pressure autoclave is charged with 50 parts of kerosene and heated to 240° C. It is then pressurized with 10 bar of carbon dioxide. Over the course of 8 hours, a mixture of 50 parts of sodium β-naphtholate and 32 parts of sodium carbonate are metered in as a suspension in kerosene via a metering pump, part of the kerosene being distilled off, condensed and transferred out of the reaction vessel at reduced pressure. After the usual workup, the 2-hydroxynaphthalene-3-carboxylic acid is obtained in a yield of 69% based on sodium β-naphtholate used. In addition, 20% of unreacted β-naphthol and small amounts of 2-hydroxynaphthalene-6-carboxylic acid and 2-hydroxynaphthalene-3,6-dicarboxylic acid are obtained.

Provenance & Evidence