HCID 19437528, compound → HCID 19437530, compound

HRID 1734393Notes

Reaction equation

HRID 1734393 reaction equation
[C:1]([O:4][CH:5]([CH3:34])[CH2:6][CH2:7][CH2:8][C:9]#[C:10][C:11]1[CH:16]=[CH:15][C:14]([C:17]2[N:22]=[CH:21][C:20]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])=[CH:19][N:18]=2)=[CH:13][CH:12]=1)(=[O:3])[CH3:2]>C(Cl)(Cl)Cl>[C:1]([O:4][CH:5]([CH3:34])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][C:14]([C:17]2[N:22]=[CH:21][C:20]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])=[CH:19][N:18]=2)=[CH:13][CH:12]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 1

HCID 19437528HCID 19437528, compound

Product 1

HCID 19437530HCID 19437530, compoundYield 98.5%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

In the same manner as above, 0.92 g (yield 98.5%) of 2-(4-(6-acetoxy-1-heptyl)phenyl)-5-decyloxypyrimidine, [α]D20 =-1.2° (c=1, chloroform), is obtained from 0.93 g of optically active 2-(4-(6-acetoxy-1-heptynyl)phenyl)-5-decyloxypyrimidine.

Sources & evidence

ORD record
ord-23158ff9f46d4e5dab50ef09b67dd785
Source dataset
uspto-grants-1996_07
Patent number
US05534188

Reaction notes

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