HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Aminopyrazin-2-yl)methanol → 3-Aminopyrazine-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Aminopyrazin-2-yl)methanol | HCID 33728543 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 3-Aminopyrazine-2-carbaldehyde | HCID 15274931 | 82% |
Reaction Steps
A suspension of 3-aminopyrazine methanol, 6.3 g (0.05 mol) and manganese dioxide (38.0 g) in 400 mL of chloroform is stirred at room temperature for two hours and the resulting solid is filtered off. The filtrate is evaporated to dryness which gives the desired product as a yellow crystalline solid, (5.00g, 82% yield) having a melting point 110°-114° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05534485 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-d49d197fbe3d423f80d381e7074a1763 |
| Source note | uspto-grants-1996_07 |