HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → 1-Benzyl-7-benzyloxy-3-hydroxymethyl-2-methylpyrrolo[2,3-d]pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 1-Benzyl-7-benzyloxy-3-formyl-2-methylpyrrolo[2,3-d]pyridazine | HCID 19437754 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Benzyl-7-benzyloxy-3-hydroxymethyl-2-methylpyrrolo[2,3-d]pyridazine | HCID 19437781 | 92% |
Reaction Steps
1.3 g (3.6 mmol) of 1-benzyl-7-benzyloxy-3-formyl-2-methylpyrrolo[2,3-d]pyridazine and 140 mg (3.7 mmol) of sodium borohydride are reacted in 125 ml of ethanol as described for Example 1a. Yield: 92%, m.p.: 130°-132° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05534515 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-c1a0692a70e044d382d157610a1781c5 |
| Source note | uspto-grants-1996_07 |