HRID1734866

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)c1ccc(C=O)cc1NC(=O)CC1c2ccccc2Oc2ccccc21

HCID19966116

未命名化合物

HCID178506591

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)c1ccc(C(O)CCCC2CCCCC2)cc1NC(=O)CC1c2ccccc2Oc2ccccc21

HCID19966299

未命名化合物

PROCEDURE

实验过程

Following a procedure similar to that described in Example 14, but using 3-cyclohexylpropylmagnesium iodide and N-(2-t-butyl-5-formylphenyl)-2-(9H-xanthen-9-yl)acetamide (prepared as described in Preparation 15) as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as a foam-like substance.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b337b221a34f454c881f5c505b99a4a0
来源数据集: uspto-grants-1996_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05534529
来源说明: uspto-grants-1996_07

反应 SMILES

[CH:1]1([CH2:7][CH2:8][CH2:9][Mg]I)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:12]([C:16]1[CH:21]=[CH:20][C:19]([CH:22]=[O:23])=[CH:18][C:17]=1[NH:24][C:25](=[O:41])[CH2:26][CH:27]1[C:40]2[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=2[O:34][C:33]2[C:28]1=[CH:29][CH:30]=[CH:31][CH:32]=2)([CH3:15])([CH3:14])[CH3:13]>>[C:12]([C:16]1[CH:21]=[CH:20][C:19]([CH:22]([OH:23])[CH2:9][CH2:8][CH2:7][CH:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)=[CH:18][C:17]=1[NH:24][C:25](=[O:41])[CH2:26][CH:27]1[C:28]2[CH:29]=[CH:30][CH:31]=[CH:32][C:33]=2[O:34][C:35]2[C:40]1=[CH:39][CH:38]=[CH:37][CH:36]=2)([CH3:15])([CH3:13])[CH3:14]