4-(Decyloxy)benzoic acid → HCID 19966052, compound

HRID 1734870Notes

Reaction equation

HRID 1734870 reaction equation
[CH2:1]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16]([OH:18])=O)=[CH:14][CH:13]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[C:21]([C:25]1[CH:31]=[CH:30][C:29]([CH2:32][CH2:33][C:34](=[O:43])[CH2:35][CH:36]2[CH2:42][CH2:41][CH2:40][CH2:39][CH2:38][CH2:37]2)=[CH:28][C:26]=1[NH2:27])([CH3:24])([CH3:23])[CH3:22]>>[C:21]([C:25]1[CH:31]=[CH:30][C:29]([CH2:32][CH2:33][C:34](=[O:43])[CH2:35][CH:36]2[CH2:42][CH2:41][CH2:40][CH2:39][CH2:38][CH2:37]2)=[CH:28][C:26]=1[NH:27][C:16](=[O:18])[C:15]1[CH:14]=[CH:13][C:12]([O:11][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])=[CH:20][CH:19]=1)([CH3:24])([CH3:22])[CH3:23]

Participants

3

Reactant 2

HCID 1385274-(Decyloxy)benzoic acidHCID 19966196HCID 19966196, compound

Product 1

HCID 19966052HCID 19966052, compound

Procedure

Following a procedure similar to that described in Example 21, but using 4-decyloxybenzoic acid and 2-t-butyl-5-(4-cycloheptyl-3-oxobutyl)aniline as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as crystals, melting at 98°-99° C. (after recrystallization from a mixture of ethyl acetate and hexane). The 2-t-butyl-5-(4-cycloheptyl-3-oxobutyl)aniline used as a starting material was prepared following a similar procedure to that described in Preparation 7, but using 2-t-butyl-5-(4-cycloheptyl-3-oxobutyl)-1-nitrobenzene (prepared by a procedure similar to that described in Preparation 6).

Sources & evidence

ORD record
ord-22126c45dacc45d2a807f66c824ea496
Source dataset
uspto-grants-1996_07
Patent number
US05534529

Reaction notes

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