反应详情

To 86 g (434 mmole) of O,O,O-triethyl thiophosphate in 300 ml of absolute ethanol was added 28 g (440 mmole) of 88% KOH. The resulting mixture was refluxed for 20 hours, filtered while warm, concentrated in vacuo, and triturated with 20% diethyl ether/80%hexanes to yield 67 g of the title compound, a white solid mp 192°-197° C.

1. temperatureThe resulting mixture was refluxed for 20 hours
2. filtrationfiltered
3. temperaturewhile warm
4. concentrationconcentrated in vacuo
5. customtriturated with 20% diethyl ether/80%hexanes