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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1735084Generated: November 3, 2026

Methyl iodide → 2-Chloro-1-methyl-1H-indole-3-carbaldehyde

https://huagongshe.com/reaction/1735084

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
Reactant2-chloro-1H-indole-3-carbaldehydeHCID 314791—
Product2-Chloro-1-methyl-1H-indole-3-carbaldehydeHCID 31479293.8%

Reaction Steps

Prepared from (1) (18 g), methyl iodide (17.1 g) and Nail (2.88 g) yielding (3) (18.2 g), m.p. 88°-90° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05536721
Source datasetuspto-grants-1996_07
ORD IDord-48f49b206e4445b9b7a5a9187b41f5b0
Source noteuspto-grants-1996_07