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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1735105Generated: November 1, 2026

Potassium Hydroxide → 4,6-Dichloro-8-methylthieno[2,3-b]indole-2-carboxylic acid

https://huagongshe.com/reaction/1735105

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
ReactantMethyl 4,6-dichloro-8-methylthieno[2,3-b]indole-2-carboxylateHCID 19068958—
Product4,6-Dichloro-8-methylthieno[2,3-b]indole-2-carboxylic acidHCID 1906894279.5%

Reaction Steps

Prepared from KOH (2.23 g), (53) (2.20 g) after reflux for 41/3 h yielding (56) 1.67 g (79.5%). M.p. 278°-281° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05536721
Source datasetuspto-grants-1996_07
ORD IDord-faa1e8c1778c405ea944b2b84e02488c
Source noteuspto-grants-1996_07