HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formamide → HCID 15838318, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | HCID 15838319 | HCID 15838319 | — |
| Product | HCID 15838318 | HCID 15838318 | — |
Reaction Steps
4-Methyl-5α-4-azaandrostan-3-on-17β-yloxyacetic acid (40 mg) and formamide (0.8 ml) were heated at 178°-180° C. under N2 for 18 hours. The mixture was cooled to room temperature and poured onto ice-water. The crude product was extracted with CH2Cl2 and dried (Na2SO4). Removal of solvent gave the crude product which was recrystallized from CH2Cl2 -hexane with trace MeOH to give title product, m.p. 222°-225° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05536727 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-a7223683c69444f88320515935c108e1 |
| Source note | uspto-grants-1996_07 |