Water → 4-(2,3-Dihydro-2,2-dimethylbenzofuran-7-ylmethyl)cyclohexanone

HRID 1735304Notes

Reaction equation

HRID 1735304 reaction equation
[CH3:1][C:2]1([CH3:22])[CH2:6][C:5]2[CH:7]=[CH:8][CH:9]=[C:10]([CH2:11][CH:12]3[CH2:21][CH2:20][C:15]4(OCC[O:16]4)[CH2:14][CH2:13]3)[C:4]=2[O:3]1.O>C(O)(=O)C>[CH3:1][C:2]1([CH3:22])[CH2:6][C:5]2[CH:7]=[CH:8][CH:9]=[C:10]([CH2:11][CH:12]3[CH2:21][CH2:20][C:15](=[O:16])[CH2:14][CH2:13]3)[C:4]=2[O:3]1

Participants

4

Reactant 2

HCID 962WaterHCID 197052578-(2,3-Dihydro-2,2-dimethylbenzofuran-7-ylmethyl)-1,4-dioxaspiro[4.5]decane

Product 1

HCID 197052604-(2,3-Dihydro-2,2-dimethylbenzofuran-7-ylmethyl)cyclohexanone

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

This compound is prepared in a manner analogous to that of Step D of Example 2, using 5.4 grams (0.018 mole) of 8-(2,3-dihydro-2,2-dimethylbenzofuran-7-ylmethyl)-1,4-dioxaspiro[4.5]decane and 25 mL of water in 100 mL of acetic acid, yielding 4-(2,3-dihydro-2,2-dimethylbenzofuran-7-ylmethyl)cyclohexanone.

Workup

  1. customThis compound is prepared in a manner analogous to that of Step D of Example 2

Sources & evidence

ORD record
ord-7218c90dc3144e66a6f5c4cb5f2f9e90
Source dataset
uspto-grants-1996_07
Patent number
US05536725

Reaction notes

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