HCID 19705195, compound → 8-(2,2,3,3-Tetrafluoro-2,3-dihydrobenzofuran-7-ylmethylene)-1,4-dioxaspiro[4.5]decane

HRID 1735310Notes

Reaction equation

HRID 1735310 reaction equation
[F:1][C:2]1([F:24])[C:6]([F:8])([F:7])[C:5]2[CH:9]=[CH:10][CH:11]=[C:12]([CH2:13][CH:14]3[CH2:23][CH2:22][C:17]4([O:21][CH2:20][CH2:19][O:18]4)[CH2:16][CH2:15]3)[C:4]=2[O:3]1>[Pd].C(O)C>[F:24][C:2]1([F:1])[C:6]([F:7])([F:8])[C:5]2[CH:9]=[CH:10][CH:11]=[C:12]([CH:13]=[C:14]3[CH2:23][CH2:22][C:17]4([O:21][CH2:20][CH2:19][O:18]4)[CH2:16][CH2:15]3)[C:4]=2[O:3]1

Participants

4

Reactant 1

HCID 19705195HCID 19705195, compound

Product 1

HCID 197052368-(2,2,3,3-Tetrafluoro-2,3-dihydrobenzofuran-7-ylmethylene)-1,4-dioxaspiro[4.5]decane

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

This compound is prepared in a manner analogous to that of Step C of Example 2, by the hydrogenation of 8.9 grams (0.026 mole) of 8-(2,2,3,3-tetrafluoro-2,3-dihydrobenzofuran-7-ylmethylene)-1,4-dioxaspiro[4.5]decane in the presence of 0.4 gram (catalyst) of 10% palladium on charcoal in 50 mL of ethanol, yielding 8-(2,2,3,3-tetrafluoro-2,3-dihydrobenzofuran-7-ylmethyl)-1,4-dioxaspiro[4.5]decane.

Workup

  1. customThis compound is prepared in a manner analogous to that of Step C of Example 2

Sources & evidence

ORD record
ord-2eba46a7ac6c426e8f690ef1803829f7
Source dataset
uspto-grants-1996_07
Patent number
US05536725

Reaction notes

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