Diethylene Glycol Monoethyl Ether → HCID 19705194, compound

HRID 1735336Notes

Reaction equation

HRID 1735336 reaction equation
[F:1][C:2]([F:18])([F:17])[C:3]1[CH:4]=C([CH:14]=[CH:15][CH:16]=1)OC1CCC(=O)CC1.[C:19]([NH:21][C:22]([NH2:24])=[NH:23])#[N:20].C(O[CH2:28][CH2:29][O:30][CH2:31][CH2:32]O)C>>[NH2:23][C:22]1[N:21]=[C:19]([NH2:20])[C:2]2[CH2:32][CH:31]([O:30][CH2:29][C:28]3[CH:14]=[CH:15][CH:16]=[C:3]([C:2]([F:1])([F:17])[F:18])[CH:4]=3)[CH2:15][CH2:16][C:3]=2[N:24]=1

Participants

4

Reactant 3

HCID 8146Diethylene Glycol Monoethyl EtherHCID 19705231HCID 19705231, compoundHCID 178418324HCID 178418324, compound

Product 1

HCID 19705194HCID 19705194, compound

Procedure

This compound is prepared in a manner analogous to that of Example 1, using 3.5 grams (0.013 mole) of 4-(3-trifluoromethylphenoxy)cyclohexanone and 1.2 grams (0.014 mole) of cyanoguanidine in 2-(2-ethoxyethoxy)ethanol, yielding 2,4-diamino-6-(3-trifluoromethylphenylmethoxy)-5,6,7,8-tetrahydroquinazoline.

Workup

  1. customThis compound is prepared in a manner analogous to that of Example 1

Sources & evidence

ORD record
ord-9d44ffcf5cb04f2aae8212f82e671afc
Source dataset
uspto-grants-1996_07
Patent number
US05536725

Reaction notes

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