HCID 19705197, compound → HCID 19705207, compound

HRID 1735342Notes

Reaction equation

HRID 1735342 reaction equation
[C:1]1([Si:7]([CH3:16])([CH3:15])[CH:8]2[CH2:13][CH2:12][C:11](=O)[CH2:10][CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:17]([NH:19][C:20]([NH2:22])=[NH:21])#[N:18]>C(OCCOCCO)C>[NH2:22][C:20]1[N:19]=[C:17]([NH2:18])[C:12]2[CH2:13][CH:8]([Si:7]([C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)([CH3:16])[CH3:15])[CH2:9][CH2:10][C:11]=2[N:21]=1

Participants

4

Reactant 2

HCID 19705197HCID 19705197, compoundHCID 178418324HCID 178418324, compound

Product 1

HCID 19705207HCID 19705207, compound

Reagents, catalysts & solvents 1

HCID 8146Diethylene Glycol Monoethyl EtherSolvent

Procedure

This compound is prepared in a manner analogous to that of Example 1, using 3.0 grams (0.013 mole) of 4-(phenyldimethylsilyl)cyclohexanone and 1.2 grams (0.014 mole) of cyanoguanidine in 2-(2-ethoxyethoxy)ethanol, yielding 2,4-diamino-6-(phenyldimethylsilyl)-5,6,7,8-tetrahydroquinazoline.

Workup

  1. customThis compound is prepared in a manner analogous to that of Example 1

Sources & evidence

ORD record
ord-1ec527a707da49d8a4f9c412b22a2e90
Source dataset
uspto-grants-1996_07
Patent number
US05536725

Reaction notes

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