1-Bromo-4-(trifluoromethoxy)benzene → 2-(4'-Trifluoromethoxybiphenyl-4-yl)-5-propylpyrimidine

Participants

Role	Name	HCID	Charge
Reactant	1-Bromo-4-(trifluoromethoxy)benzene	HCID 521008	—
Reactant	2-(4-Bromophenyl)-5-propylpyrimidine	HCID 13651450	—
Product	2-(4'-Trifluoromethoxybiphenyl-4-yl)-5-propylpyrimidine	HCID 14438452	—

Reaction Steps

Analogously to Example 9 , by reacting 14.0 g of 2-(4-bromophenyl)-5-propylpyrimidine and 12.1 g of trifluoromethoxy-4-bromobenzene, the corresponding 2-(4'-trifluoromethoxybiphenyl-4-yl )-5-propylpyrimidine having C 125° SG 1110 SA 218° I is obtained.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05536442
Source dataset	uspto-grants-1996_07
ORD ID	ord-0504ded8d53b4732a31ae4d77bf4ef0f
Source note	uspto-grants-1996_07