HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Benzylaminocarbonyl-L-prolyl-L-proline benzyl ester → N-(Benzylaminocarbonyl)-L-prolyl-L-proline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Benzylaminocarbonyl-L-prolyl-L-proline benzyl ester | HCID 54203628 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-(Benzylaminocarbonyl)-L-prolyl-L-proline | HCID 53876803 | 99.9% |
Reaction Steps
Palladium-black (0.87 g) was added to a solution of N-(benzylaminocarbonyl)-L-prolyl-L-proline benzyl ester (43.55 g) in THF (400 ml), and the mixture was stirred at room temperature overnight under a hydrogen atmosphere. The reaction mixture was filtered and concentrated to give the title compound (34.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05536737 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-4bd92b604c7e41169933f68401d3dfbc |
| Source note | uspto-grants-1996_07 |