HRID1735419

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(O)CC[C@@H](O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)[C@H]3CC[C@]12C

HCID5459840

20-Hydroxyecdysone

C27H44O7

结构：CC(C)(C)[Si](C)(C)OCCC(O)[C@@H]1CSCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1

HCID67745447

未命名化合物

PRODUCTS

生成物

HCID53648898

未命名化合物

收率 48.9%

PROCEDURE

实验过程

(R)-4-[3-(tert-Butyldimethylsilyloxy)-1-hydroxypropyl]-3[[(S)-1-(phenylmethyloxycarbonyl)-2-pyrrolidinyl]carbonyl]thiazolidine (1.44 g) was subjected to the same reaction as in Example 20-e) to give the title compound (701 mg).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7197617371ea40b78955950f78c24716
来源数据集: uspto-grants-1996_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05536737
来源说明: uspto-grants-1996_07

反应 SMILES

[Si:1]([O:8][CH2:9][CH2:10][CH:11]([C@@H:13]1[CH2:17][S:16][CH2:15][N:14]1[C:18]([C@@H:20]1[CH2:24][CH2:23][CH2:22][N:21]1[C:25]([O:27][CH2:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)=[O:26])=[O:19])[OH:12])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].C[C@@]12[C@@H]([C@@](O)([C@H](O)CCC(O)(C)C)C)CC[C@@]1(O)C1=CC([C@@H]3C[C@@H](O)[C@@H](O)C[C@]3(C)[C@H]1CC2)=O>>[Si:1]([O:8][CH2:9][CH2:10][C:11]([C@@H:13]1[CH2:17][S:16][CH2:15][N:14]1[C:18]([C@@H:20]1[CH2:24][CH2:23][CH2:22][N:21]1[C:25]([O:27][CH2:28][C:29]1[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=1)=[O:26])=[O:19])=[O:12])([C:4]([CH3:7])([CH3:5])[CH3:6])([CH3:3])[CH3:2]