HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrole → 2,2'-(2,2,3,3,4,4,4-Heptafluorobutane-1,1-diyl)di(1H-pyrrole)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrole | HCID 8027 | — |
| Reactant | Heptafluorobutyraldehyde | HCID 67809 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2,2'-(2,2,3,3,4,4,4-Heptafluorobutane-1,1-diyl)di(1H-pyrrole) | HCID 10470855 | — |
Reaction Steps
Pyrrole (2; 50 mmol) and heptafluorobutyraldehyde (7; R=CF3CF2, as the hydrate, 25 mmol) were condensed in tetrahydrofuran in the presence of acid catalyst as described above to give bis-(pyrrol-2-yl) heptafluoroprop-1-ylmethane (8; R=CF3CF2) in >50% isolated yield. GCMS m/z; 314 (M+, 22%), 145 (100%); 1H NMR (δ, CDCl3 at 7.24); 4.92 (t, 1H), 6.22 (d, 4H), 6.75 (s, 2H), 8.07 (bs, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05536844 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-566c6d6dcd3d492b937f28e9495adc8c |
| Source note | uspto-grants-1996_07 |