Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(Thiophen-2-yl)propan-2-amine → N-[1-Methyl-1-(2-thienyl)ethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(Thiophen-2-yl)propan-2-amine | HCID 45099 | — |
| 반응물 | S-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylate | HCID 15380265 | — |
| 생성물 | N-[1-Methyl-1-(2-thienyl)ethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide | HCID 22862418 | 88% |
반응 단계
Following a procedure similar to that described in Example 3(b), but using S-2-pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 1-methyl-1-(2-thienyl)ethylamine (prepared as described in Preparation 11a) as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 88%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05536714 |
| 출처 데이터셋 | uspto-grants-1996_07 |
| ORD ID | ord-66e178d4320d4995982374d427299c92 |
| 출처 메모 | uspto-grants-1996_07 |