Methyl 2-Methoxybenzoate → 2-(2-Methoxyphenyl)propan-2-amine

HRID 1735554Notes

Reaction equation

HRID 1735554 reaction equation
CO[C:3]1[CH:8]=[CH:7][C:6]([C:9]([NH2:12])([CH3:11])[CH3:10])=[CH:5][CH:4]=1.[CH3:13][O:14]C1C=CC=CC=1C(OC)=O>>[CH3:13][O:14][C:5]1[CH:4]=[CH:3][CH:8]=[CH:7][C:6]=1[C:9]([NH2:12])([CH3:10])[CH3:11]

Participants

3

Reactant 2

HCID 61151Methyl 2-MethoxybenzoateHCID 110082782-(4-Methoxyphenyl)propan-2-amine

Product 1

HCID 153108562-(2-Methoxyphenyl)propan-2-amineYield 81%

Procedure

Following a procedure similar to that described in Preparation 10a, but using methyl 2-methoxybenzoate as a starting material, in a relative amount similar to that used in that Preparation, the title compound was obtained in a yield of 81%.

Workup

  1. customin a relative amount similar to that used in that Preparation

Sources & evidence

ORD record
ord-0dc4289a4499490e94fe938314e2dc7d
Source dataset
uspto-grants-1996_07
Patent number
US05536714

Reaction notes

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