Methyl 3,4-Dimethoxybenzoate → 2-(3,4-Dimethoxyphenyl)propan-2-amine

HRID 1735555Notes

Reaction equation

HRID 1735555 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]([NH2:12])([CH3:11])[CH3:10])=[CH:5][CH:4]=1.[CH3:13][O:14]C1C=C(C=CC=1OC)C(OC)=O>>[CH3:13][O:14][C:4]1[CH:5]=[C:6]([C:9]([NH2:12])([CH3:10])[CH3:11])[CH:7]=[CH:8][C:3]=1[O:2][CH3:1]

Participants

3

Reactant 2

HCID 16522Methyl 3,4-DimethoxybenzoateHCID 110082782-(4-Methoxyphenyl)propan-2-amine

Product 1

HCID 30322332-(3,4-Dimethoxyphenyl)propan-2-amineYield 61%

Procedure

Following a procedure similar to that described in Preparation 10a, but using methyl 3,4-dimethoxybenzoate, in a relative amount similar to that used in that Preparation, the title compound was obtained in a yield of 61%.

Workup

  1. customin a relative amount similar to that used in that Preparation

Sources & evidence

ORD record
ord-fc7c7f5e3fec49f885a75acdd7bb02a2
Source dataset
uspto-grants-1996_07
Patent number
US05536714

Reaction notes

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