HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,6-Bis(phenylmethoxy)-1H-indole → 5,6-Dihydroxyindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,6-Bis(phenylmethoxy)-1H-indole | HCID 20920 | — |
| Reactant | 5,6-Diacetoxyindole | HCID 3805883 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5,6-Dihydroxyindole | HCID 114683 | — |
Reaction Steps
In a first stage, 5,6-diacetoxyindole and 5,6-dibenzyloxyindole are prepared by means of a cyclizing reduction. In the case of 5,6-dibenzyloxyindole the cyclizing reduction is carried out using iron in the presence of acetic acid. In a second stage, 5,6-dihydroxyindole is obtained:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05536865 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-df9f2491c8c54926a1cae643206f11a7 |
| Source note | uspto-grants-1996_07 |