HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54502549, compound → HCID 54043890, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54502549 | HCID 54502549 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 54043890 | HCID 54043890 | 94.5% |
Reaction Steps
A solution of benzyl (2R)-2-(piperidinocarbonylmethyl)-4-methylvalerate (0.625 g) in methanol (10 ml) was hydrogenated over 10% palladium on carbon (80 mg) at 3 atmospheric pressure of hydrogen for 1 hour. After removal of the catalyst by filtration, the filtrate was concentrated in vacuo to give (2R)-2-(piperidinocarbonylmethyl)-4-methylvaleric acid (0.43 g) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05538950 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-33ac758af619439e822a8dea18547e17 |
| Source note | uspto-grants-1996_07 |