3-Fluoro-4-nitrobenzyl bromide → 5-[N-(4-Cyanophenyl)-N-(3-fluoro-4-nitrobenzyl)amino]pyrimidine

HRID 1735784Notes

Reaction equation

HRID 1735784 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10]2[CH:11]=[N:12][CH:13]=[N:14][CH:15]=2)=[CH:5][CH:4]=1)#[N:2].[F:16][C:17]1[CH:18]=[C:19]([CH:22]=[CH:23][C:24]=1[N+:25]([O-:27])=[O:26])[CH2:20]Br>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([C:10]2[CH:15]=[N:14][CH:13]=[N:12][CH:11]=2)[CH2:20][C:19]2[CH:22]=[CH:23][C:24]([N+:25]([O-:27])=[O:26])=[C:17]([F:16])[CH:18]=2)=[CH:5][CH:4]=1)#[N:2]

Participants

3

Reactant 2

HCID 27746613-Fluoro-4-nitrobenzyl bromideHCID 105358714-(Pyrimidin-5-ylamino)benzonitrile

Product 1

HCID 106891225-[N-(4-Cyanophenyl)-N-(3-fluoro-4-nitrobenzyl)amino]pyrimidine

Procedure

Starting compounds: 5-[N-(4-cyanophenyl) amino]pyrimidine and 3-fluoro-4-nitrobenzyl bromide

Sources & evidence

ORD record
ord-d4821fdd92d74f7cb6bea2372bf82fa7
Source dataset
uspto-grants-1996_07
Patent number
US05538976

Reaction notes

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