HuagongsheHuagongshe Chemistry Print Report · For research reference only
phenylalaninol, (S)- → HCID 22862764, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | phenylalaninol, (S)- | HCID 447213 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | (S)-2-((tert-Butoxycarbonyl)amino)-3,3-dimethylbutanoic acid | HCID 2734668 | — |
| Reactant | HCID 178418300 | HCID 178418300 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22862764 | HCID 22862764 | — |
Reaction Steps
25 g of tert-butyloxycarbonyl-L-tert-leucine are dissolved in 250 ml of dry dimethylformamide, 16.36 g of phenylalaninol, 14.62 g of hydroxybenzotriazole and 24.9 g of N-ethyl-N'-(3-dimethylaminopropyl)carbodiimide hydrochloride are added. The mixture is stirred for one day. The precipitate is filtered off, washed carefully with ethyl acetate and dried in vacuo (m.p. 198°-201°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05538997 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-2628263c641d483a9e12d06b78fda069 |
| Source note | uspto-grants-1996_07 |