Sodium Hydroxide → HCID 19699594, compound

HRID 1735902Notes

Reaction equation

HRID 1735902 reaction equation
[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH:2]1[N:11]1[CH:15]=[CH:14][N:13]([CH2:16][C:17]2[CH:26]=[CH:25][C:20]([C:21]([O:23]C)=[O:22])=[CH:19][CH:18]=2)[C:12]1=[S:27].[OH-].[Na+]>>[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH:2]1[N:11]1[CH:15]=[CH:14][N:13]([CH2:16][C:17]2[CH:18]=[CH:19][C:20]([C:21]([OH:23])=[O:22])=[CH:25][CH:26]=2)[C:12]1=[S:27]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 19699633HCID 19699633, compound

Product 1

HCID 19699594HCID 19699594, compound

Procedure

substituting methyl 4-[3-(1,2,3,4-tetrahydronaphthalen-2-yl)-2-thioxo-2,3-dihydro-1H-imidazol -1-ylmethyl]benzoate and sodium hydroxide gave 4-[3-(1,2,3,4-tetrahydronaphthalen-2-yl)-2-thioxo-2,3-dihydro-1H-imidazol-1-ylmethyl]benzoic acid, m.p. 211°-212° C.;

Sources & evidence

ORD record
ord-4c365788c6cb44bc9429e880ba5fe5b3
Source dataset
uspto-grants-1996_07
Patent number
US05538988

Reaction notes

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