Hydrogen Peroxide → 2-Hexyloxirane

Participants

Reaction Steps

To a mechanically stirred suspension (50° C.) of immobilized C. antarctica lipase (1 g, according to example 1) in 1-octene (15 ml, ca. 95.4 mmol) containing myristic acid (4.356 g, 19.1 mmol) was hydrogen peroxide (8 ml 60% (w/v)) added in four equal portions after 0, 1.5, 3 and 4.5 hours (140 mmol in all). After 6 hours 51% octene oxide was formed as determined by gas chromatography.

Provenance & Evidence