3-(ethylthio)-5-fluoro-3-(2-hydroxyethyl)-1,3-dihydro-2(2H)-indolone → 3-(Ethylthio)-5-fluoro-3-{2-[4-(7-methoxy-1,2,3,4-tetrahydro-1-naphthyl)-1-piperazinyl]ethyl}-1,3-dihydro-2(2H)-indolone
Reaction equation
[CH2:19]([CH3:20])[S:21][C:22]1([CH2:33][CH2:34][OH:35])[C:23](=[O:32])[NH:24][c:25]2[cH:26][cH:27][c:28]([F:31])[cH:29][c:30]21.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:11]([cH:12]1)[CH:10]([N:13]1[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]1)[CH2:9][CH2:8][CH2:7]2>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:11]([cH:12]1)[CH:10]([N:13]1[CH2:14][CH2:15][N:16]([CH2:34][CH2:33][C:22]3([S:21][CH2:19][CH3:20])[C:23](=[O:32])[NH:24][c:25]4[cH:26][cH:27][c:28]([F:31])[cH:29][c:30]43)[CH2:17][CH2:18]1)[CH2:9][CH2:8][CH2:7]2Participants
3
Sources & evidence
- ORD record
- ord-fbcc8604855c44818ee2f214a0358ac0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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