HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methoxycarbonyl)-2-nitrobenzoic acid → 2-Amino-4-(methoxycarbonyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methoxycarbonyl)-2-nitrobenzoic acid | HCID 21906474 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-4-(methoxycarbonyl)benzoic acid | HCID 13349386 | 65.4% |
Reaction Steps
A solution of methyl 4-carboxy-3-nitrobenzoate (3 g, 13.3 mM) in ethanol (20 ml) was hydrogenated at atmospheric pressure in the presence of 10% palladium-carbon (1 g) for 40 minutes. After filtration of the catalyst, the solid was recrystallised from ethanol to give methyl 3-amino-4-carboxybenzoate (1.7 g, 65%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05541178 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-0706760626d84f33bc986c666f3f9c1a |
| Source note | uspto-grants-1996_07 |