Methyl iodide → HCID 19432689, compound

HRID 1736392Notes

Reaction equation

[Cl:1][C:2]1[CH:41]=[CH:40][C:39]([O:42][CH3:43])=[CH:38][C:3]=1[O:4][C:5]1[C:6]([O:25][CH2:26][CH2:27][O:28][C:29](=[O:37])[NH:30][C:31]2[CH:32]=[N:33][CH:34]=[CH:35][CH:36]=2)=[N:7][CH:8]=[N:9][C:10]=1[NH:11][S:12]([C:15]1[CH:24]=[CH:23][C:18]2[O:19][CH2:20][CH2:21][O:22][C:17]=2[CH:16]=1)(=[O:14])=[O:13].[CH3:44][I:45]>>[I-:45].[Cl:1][C:2]1[CH:41]=[CH:40][C:39]([O:42][CH3:43])=[CH:38][C:3]=1[O:4][C:5]1[C:6]([O:25][CH2:26][CH2:27][O:28][C:29]([NH:30][C:31]2[CH:32]=[N+:33]([CH3:44])[CH:34]=[CH:35][CH:36]=2)=[O:37])=[N:7][CH:8]=[N:9][C:10]=1[NH:11][S:12]([C:15]1[CH:24]=[CH:23][C:18]2[O:19][CH2:20][CH2:21][O:22][C:17]=2[CH:16]=1)(=[O:13])=[O:14]

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 70347305HCID 70347305, compound

Product 1

HCID 19432689HCID 19432689, compound

Procedure

By alkylating the compound from Example 1, part a), with methyl iodide there was obtained 3-[2-[5-(2-chloro-5-methoxy-phenoxy)-6-(2,3-dihydro- 1,4-benzodioxin-6-ylsulfonylamino)-pyrimidin-4-yloxy]-ethoxycarbonylamino]- 1 -methyl-pyridinium iodide.

Sources & evidence

ORD record: ord-314a57603df34a36b53af98937da7660
Source dataset: uspto-grants-1996_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05541186

Reaction notes

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