HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyclopropylaniline → Ammonium Hydroxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyclopropylaniline | HCID 12253927 | — |
| Reactant | 4-Cyclopropylbenzene-1-sulfonyl chloride | HCID 22049882 | — |
| Product | Ammonium Hydroxide | HCID 14923 | — |
| Product | 4-Cyclopropylbenzene-1-sulfonamide | HCID 19432748 | — |
Reaction Steps
4-cyclopropylaniline (Bull. Soc. Chim. Belg. 1975, 84, 1197) was diazotized and converted with SO2 /Cu2Cl2 (3 hours, room temperature) into the corresponding 4-cyclopropylbenzenesulfonyl chloride. Subsequent aminolysis with ammonium hydroxide yielded the corresponding 4-cyclopropylbenzenesulfonamide, m.p. 158°-168° C., which was finally converted with KOH in EtOH in to the potassium salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05541186 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-28b71e0f1db34c638ad3f10f95e68c53 |
| Source note | uspto-grants-1996_07 |