Alumina → HCID 15069167, compound

HRID 1736773Notes

Reaction equation

[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[C:18]([C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:13][CH:12]=2)[C:8]2[C:30]([O:35][CH2:36][CH2:37]OC)=[CH:31][CH:32]=[C:33]([CH3:34])[C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4].[O-2].[Al+3].[O-2].[O-2].[Al+3].C(Cl)Cl.[CH2:48](O)[CH3:49]>>[CH2:36]([O:35][C:30]1[C:8]2[N:9]([CH2:10][C:11]3[CH:12]=[CH:13][C:14]([C:17]4[C:18]([C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=4)=[CH:15][CH:16]=3)[C:5]([CH2:1][CH2:2][CH2:3][CH3:4])=[N:6][C:7]=2[C:33]([CH3:34])=[CH:32][CH:31]=1)[CH2:37][CH2:48][CH3:49]

Participants

Reactant 3

HCID 9989226Alumina

HCID 21584144Dichloromethane ethanol

HCID 67572791HCID 67572791, compound

Product 1

HCID 15069167HCID 15069167, compound

Procedure

tert.butyl 4'-[(2-n-butyl-7-(2-methoxyethoxy)-4-methyl-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate oil, Rf value: 0.35 (Aluminium oxide plate: methylene chloride/ethanol=99:1)

Sources & evidence

ORD record: ord-f72964fd4dd14991a9482952e89e6fe3
Source dataset: uspto-grants-1996_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05541229

Reaction notes

Loading…