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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1736783Generated: October 25, 2026

Trifluoroacetic acid methylene chloride → 4'-[(2-(4-Hydroxyphenyl)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylic acid

https://huagongshe.com/reaction/1736783

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acid methylene chlorideHCID 21863450—
ReactantTert.butyl 4'-[(2-(4-hydroxyphenyl)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylateHCID 136333559—
Product4'-[(2-(4-Hydroxyphenyl)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylic acidHCID 135992482—

Reaction Steps

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-(4-hydroxyphenyl)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid/methylene chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05541229
Source datasetuspto-grants-1996_07
ORD IDord-1be4e69c43f64f909b66480cc758f3d9
Source noteuspto-grants-1996_07