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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 173689Generated: October 26, 2026

1,2-Dichloroethane → 3,3-Difluoro-1'-[3-(methyloxy)-4-nitrophenyl]-1,4'-bipiperidine

https://huagongshe.com/reaction/173689

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantAcetic AcidHCID 176—
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
ReactantTriethylamineHCID 8471—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant3,3-DifluoropiperidineHCID 2758350—
Reactant1-(3-Methoxy-4-nitrophenyl)piperidin-4-oneHCID 25918857—
Product3,3-Difluoro-1'-[3-(methyloxy)-4-nitrophenyl]-1,4'-bipiperidineHCID 59441864—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-afe3f451521e477ab1f7f8c04e371a0f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)